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Kate Law, Cancer Research UK's director of clinical research, says: "We now need accurate tests that will predict which women will most benefit from anastrozole and those who will have the fewest side effects." The charity has been funding the IBIS II trial for over 10 years. Prof. Cuzick was also on a panel that published a review about the future of breast cancer prevention in Lancet Oncology in March 2011. The panel agreed that all women with a higher than 4% above average risk of getting breast cancer in the next 10 years should be offered preventive measures and close monitoring.
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Post-menopausal women with hormone receptor-positive metastatic breast cancer may have a new treatment option that could lengthen their lives, according to results of a study by the SWOG clinical trials network that were presented at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium. The combination of the two anti-estrogen drugs anastrozole and fulvestrant used in the SWOG S0226 trial extended the median survival time of women with breast cancer by more than six months compared to those who underwent standard treatment with anastrozole alone (47.7 months vs 41.3 months). The combination therapy also lengthened the median time to disease progression (15 months vs 13.5 months).
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